Application of whole body plethysmography for assessment of pulmonary function in patients with asthma and obesity

The incidence of asthma and obesity is constantly increasing. It commonly acknowledged that can make more severe poorly controlled. Conventional spirometry, despite being a “gold standard” in diagnostics lung diseases, cannot provide information on residual volume bronchial resistance, which be key to understanding the mechanics spirometric deviations found asthma-obesity phenotype. aim. To evaluate pulmonary function patients with by non-invasive safe clinical method – body plethysmography. Methods. 46 women were enrolled into study, 21 obese 25 had normal weight. 18 20 weight selected as controls. All postmenopausal. Body plethysmography was performed MasterScreen device, CareFusion, Germany. Results. Asthma associated decrease forced vital capacity an increase volume. Also, Gensler index peak expiration flows at 25, 50, 75% decreased. Interestingly, specific effective resistance without 30 40% higher than control group. In obesity, 2,5 times Residual have strong positive correlation. Conclusion. similar changes, only marked resistance. This finding related energy load breathing process asthma.